Direct oral anticoagulants: When to consider laboratory testing?
نویسندگان
چکیده
منابع مشابه
Laboratory Monitoring of Direct Oral Anticoagulants
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متن کاملThe laboratory and the direct oral anticoagulants.
Although direct oral anticoagulants do not need laboratory testing for dose adjustment, there are instances when laboratory measurement of the drug anticoagulant effect may be useful. They include before initiation of treatment, before surgical or invasive procedures, on the occasion of hemorrhagic or thrombotic events, and whenever immediate reversal of anticoagulation is needed. Choice of tes...
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Hypercoagulability can result from a variety of inherited and, more commonly, acquired conditions. Testing for the underlying cause of thrombosis in a patient is complicated both by the number and variety of clinical conditions that can cause hypercoagulability as well as the many potential assay interferences. Using an algorithmic approach to hypercoagulability testing provides the ability to ...
متن کاملBlood Spotlight The laboratory and the direct oral anticoagulants
The direct oral anticoagulants (DOAC), which include the thrombin inhibitor dabigatran and the anti-Xa agents rivaroxaban, apixaban, and edoxaban, are in clinical use in many countries (Figure 1). Clinical trials have shown that DOAC, unlike vitamin K antagonists (VKA), are effective and safe when administered without dose adjustment based on laboratory testing. However, it is a misconception t...
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Haematuria is a common finding in children. It is important to identify the underlying cause whenever possible so that appropriate follow-up is organised, particularly if the child is at risk of developing renal impairment or renal failure in later life. Until recently nephrologists relied on renal biopsy with examination under the electron microscope to make a diagnosis, but genetic testing ca...
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ژورنال
عنوان ژورنال: International Journal of Laboratory Hematology
سال: 2018
ISSN: 1751-5521
DOI: 10.1111/ijlh.12816